coronary heart disease hazard ratio of low-ranking white-collar workers of both sexes exposed to work stress, with the values of 1.33 for all ages, 1.68 for ages between 37 and 49, and 1.13 for ages between 50 and 60, all against a ratio of 1.00 for the same cohorts not exposed to stress

Work stress: a significant cause of coronary heart disease, particularly for employees under the age of 50 (see  Job stress causes heart disease).

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